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Programme overview Plenary Lectures Symposia Public Lecture Young Physiologists' Symp
Local and systemic implications of epithelial transport regulation

Epithelia & Membrane Transport Epithelia & Membrane Transport

Organised by Christoph Korbmacher, Friedrich-Alexander-University of Erlangen-Nürnberg (FAU), Germany
and Richard Boyd, University of Oxford, UK

Tuesday 12 July 2011
LT6 (Experimental Psychology B)

Epithelial transport has to be closely regulated by local and systemic mediators to fulfil the needs of individual tissues and to serve in the context of overall body homeostasis. Using a range of examples this symposium wants to illustrate the local and systemic implications of epithelial transport regulation in health and disease with an emphasis on the complex cellular and molecular mechanisms involved.

Joint International Exchange Symposium with the German Physiological Society (Deutschen Physiologischen Gesellschaft)

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08.45 Welcome and introduction by the organisers
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Tales of tails: AE1 and its polarized pathway

  Fiona Karet, University of Cambridge, UK
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Renal acid excretion – mechanisms and diseases

  Carsten Wagner, University of Zürich, Switzerland
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Extracellular nucleotides and renal function

  Robert Unwin, University College London, UK
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Cleavage as a signal to activate the epithelial sodium channel (ENaC)

  Christoph Korbmacher, Friedrich-Alexander-University of Erlangen-
Nürnberg (FAU), Germany
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10.30 Refreshments
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BLINaC: a novel epithelial Na+ channel in the liver

  Stefan Gründer, RWTH Aachen University, Germany
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Proton-assisted amino acid transporters: novel intracellular regulators of mTORC1 signalling in health and disease

  Deborah Goberdhan, University of Oxford, UK
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Concluding remarks by the organisers

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