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Programme
Programme overview Plenary Lectures Symposia Public Lecture Young Physiologists' Symp
 
Proton signals and sensors

Metabolism & Endocrinology Metabolism & Endocrinology

Organised by Richard Vaughan-Jones, University of Oxford, UK

Tuesday 12 July 2011
LT5 (Lecture theatre Le Gros Clark)

Protons (H+-ions) are universal products of metabolism that powerfully modulate cell proliferation, development,and regulatory function. This symposium addresses the emerging molecular mechanisms for H+- ion sensing and signalling in cells. Novel mechanisms include H+-activated G-protein coupled receptors, specific ion channels & transporters, and pH- transducing enzymes, all of which co-ordinate primary cell function in a highly evolved and sophisticated manner. The symposium will highlight major developments in our understanding of this fundamental signalling system.

Physiology 2011
Physiology 2011
08.45 Welcome and introduction by the organiser
Physiology 2011
09.00

Molecular mechanism and function of acid-sensing channels (ASICS)

  Michel Lazdunski, Université Nice Sophia Antipolis, France
Physiology 2011
09.30

G protein-coupled proton receptors: Expression, characterisation & function

  Klaus Seuwen, Novartis Institutes for BioMedical Research, Basel, Switzerland
Physiology 2011
10.00
x

Role of carbonic anhydrase IX in the control of intracellular and extracellular pH in three-dimensional tumourcell growths

  Pawel Swietach, University of Oxford, UK
Physiology 2011
10.30 Refreshments
Physiology 2011
11.15
x

Proton translocation by the voltage-gated proton channel Hv1: insights from molecular simulations

  Mark Sansom, University of Oxford, UK
Physiology 2011
11.45
x

Proton-coupled Ca2+ signaling in heart: role of Na+-H+ exchange, mitochondria, and the L-type Ca2+ channel

  Richard Vaughan-Jones, University of Oxford, UK
Physiology 2011
Physiology 2011
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