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Smooth muscle and endothelial cell signaling microdomains: Implications for vascular function
Physiology 2011

Vascular & Smooth Muscle Physiology Vascular & Smooth Muscle Physiology

Organised by Ron Lynch, University of Arizona, Tucson, USA
and Christopher Garland, University of Oxford, UK

Tuesday 12 July 2011
Lecture theatre to be confirmed

This symposium will present recent research attempting to define and link cellular signalling microdomains to the integration of physiological function in the vasculature.

Topics to be addressed will focus on calcium and cAMP signalling, and include novel pathways involving acid-sensitive stores, the role of membrane rafts and caveolae in focusing cell signaling proteins, signalling microdomains in vascular endothelial and smooth muscle cells and the regulation of, in particular, TRP and potassium channels and Na/K ATPases.

Physiology 2011
Physiology 2011
08.45 Welcome and introduction by the organisers
Physiology 2011

NAADP mediated local calcium signaling via endolysosomal two-pore channels

  Anthony Galione, University of Oxford, UK
Physiology 2011

Cardiovascular rafts and caveolae: signalling and protection

  Paul Insel, University of California, San Diego, USA
Physiology 2011

Local calcium signaling through TRPV4 channels and IP3Rs in the vascular endothelium

  Mark Nelson, University of Vermont, USA
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10.30 Refreshments
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Endothelial cell microdomains and integrated vascular dilatation

  Kim Dora, University of Oxford, UK
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Organization of calcium signalling pathways in smooth muscle

  Ron Lynch, University of Arizona, Tucson, USA
Physiology 2011
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