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Vascular & Smooth Muscle Physiology |
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Organised by Ron Lynch, University of Arizona, Tucson, USA
and Christopher Garland, University of Oxford, UK
Tuesday 12 July 2011
Lecture theatre to be confirmed
This symposium will present recent research attempting to define and link cellular signalling microdomains to the integration of physiological function in the vasculature.
Topics to be addressed will focus on calcium and cAMP signalling, and include novel pathways involving acid-sensitive stores, the role of membrane rafts and caveolae in focusing cell signaling proteins, signalling microdomains in vascular endothelial and smooth muscle cells and the regulation of, in particular, TRP and potassium channels and Na/K ATPases. |
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| 08.45 |
Welcome and introduction by the organisers |
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| 09.00 |
NAADP mediated local calcium signaling via endolysosomal two-pore channels
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Anthony Galione, University of Oxford, UK |
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09.30
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Cardiovascular rafts and caveolae: signalling and protection
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Paul Insel, University of California, San Diego, USA |
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10.00
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Local calcium signaling through TRPV4 channels and IP3Rs in the vascular endothelium
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Mark Nelson, University of Vermont, USA |
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| 10.30 |
Refreshments |
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| 11.15 |
Endothelial cell microdomains and integrated vascular dilatation
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Kim Dora, University of Oxford, UK |
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| 11.45 |
Organization of calcium signalling pathways in smooth muscle
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Ron Lynch, University of Arizona, Tucson, USA |
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